Blog entry by Meguid El Nahas

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by Meguid El Nahas - Sunday, 24 April 2016, 9:04 PM
Anyone in the world

http://www.ncbi.nlm.nih.gov/pubmed/27061677

The latest analysis by the Non-Communicable Disease worldwide collaboration gives an intriguing picture of the prevalence of Diabetes Mellitus (DM) worldwide.

Age-standardised prevalence, shows:

NO increase in prevalence of DM from 1980 to 2014 in Europe!

NO overall increase in Africa

NO increase in Central and Latin America

NO increase in Japan

Significant increase in the Middle East and North Africa

Significant increase in Central Asia

So how can we explain the absence of increase in the prevalence of DM in Europe, Central and Latin America or Japan where the prevalence of OBESITY has considerably increased, along with other regions of the world?!

http://www.ncbi.nlm.nih.gov/pubmed/25391910

Does this mean that the “epidemic” of DM is only due in Europe, Latin America, Japan and parts of Asia to the ageing of the populations and not Obesity….?!

On the other hand, genetic factors may explain the rise in the prevalence of DM in the Middle East, North Africa as well as in Polynesia? In these regions, DM (mainly T2DM) may be a two hit phenomenon where genetic predisposition combined with environmental factors, such as diet and obesity, may be required for the phenotypic expression of the disease.

Is the dogma linking DM and Obesity a geographical phenomenon that doesn't apply to Europe?

Is the increase prevalence of DM in Europe merely the reflection of the ageing of the population?

Is it time to rethink the “association” linking obesity to Diabetes mellitus?

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