Blog entry by Meguid El Nahas

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by Meguid El Nahas - Wednesday, 9 May 2012, 8:58 AM
Anyone in the world

DAY2 MASTER CLASS IN KHARTOUM:

CRITICAL APPRAISAL SESSIONĀ 

MAJOR HIGHLIGHT:

DO NOT EQUATE eGFR with mGFR!!!!!!

eGFR is subject to all the confounders of changes in serum creatinine:
Diet, metabolism, GFR and Tubular secretion

MEASURED GFR IS THE ONLY MARKER OF CHANGES IN GFR AND SHOULD BE USED IN CLINICAL TRIALS TO ASSESS CKD PROGRESSION!!!!

The question is:

WHY ARE NEPHROLOGISTS RELUCTANT TO MEASURE TRUE GFR IN CLINICAL TRIALS OF CKD PROGRESSION????

Is it convenience?

Is it pressure from Sponsors to fudge the real result?

Is it just ignorance that eGFR is an inadequate marker of true GFR?

I am bewildered....!!!!!

[ Modified: Thursday, 1 January 1970, 1:00 AM ]