OLA Blog

ASN 2018: Richard Glassock Blog

Written by Meguid El Nahas on Sunday, 05 November 2017. Posted in OLA Blog

ASN 2018: Richard Glassock Blog
It is impossible to capture the "leading news" from the ASN meeting -  it is simply too immense-In my field of glomerular disease, I would gave to pick out the CARDINAL and MENTOR trial findingsCARDINAL is a randomized placebo controlled...

RCTs in CKD: A Warning Box!

Written by Meguid El Nahas on Thursday, 26 October 2017. Posted in OLA Blog

RCTs in CKD: A Warning Box!
The majority of RCTs in Nephrology are flawed and invalid for a range of reasons: https://link.springer.com/content/pdf/bfm%3A978-3-319-10292-4%2F1.pdf Having said that, Nephrology journals continue to publish such trials and mostly small,...

Sleep-Time Hypertension: A major CKD-CVD Risk Factor

Written by Meguid El Nahas on Thursday, 26 October 2017. Posted in OLA Blog

Sleep-Time Hypertension: A major CKD-CVD Risk Factor
the MAPEC spanish propsective study of ~5,000 individual showed that sleep-time hypertension rather than casual-clinic BP or 24h ABPM was the independent risk factor for incident CKD. https://www.ncbi.nlm.nih.gov/pubmed/28455314 Previous studies...

World Kidney Day 2018

Written by Meguid El Nahas on Friday, 29 September 2017. Posted in OLA Blog

World Kidney Day 2018
http://www.worldkidneyday.org/2018-campaign/2018-wkd-theme/ The World Kidney Day (WKD) theme for 2018 is:"Kidneys & Women's Health"... I am not sure what this means...am i to expect the theme in 2019 to be... "Kidneys & Men's Health......

SPRINT Cost Effectiveness: Lower BP or Better Diuretic Therapy?!

Written by Meguid El Nahas on Tuesday, 05 September 2017. Posted in OLA Blog

SPRINT Cost Effectiveness: Lower BP or Better Diuretic Therapy?!
 N Engl J Med. 2017 Aug 24;377(8):745-755. doi: 10.1056/NEJMsa1616035. Cost-Effectiveness of Intensive versus Standard Blood-Pressure Control....

Nephrology Guidelines: Are they Safe...?!

Written by Meguid El Nahas on Friday, 11 August 2017. Posted in OLA Blog

Nephrology Guidelines: Are they Safe...?!
Are Nephrology Guidelines fit  for purpose or are they: 1. Too US Centric like the latest KDIGO Kidney Donors Guidelines 2. Too overlooking of low and middle economies healthcare priorities... 3. Too Pharma Friendly... 4. Too "KOL"...

Myths in Nephrology

Written by Meguid El Nahas on Wednesday, 26 July 2017. Posted in OLA Blog

Myths in Nephrology
A Myth is a widely held but false belief or idea. Nephrology is full of Myths that are peddled and believed without valid supporting evidence; some are based on animal experimentation without supporting evidence in man. Some are simply...

Glifozins & Cardioprotection: Another Myth in the Making...!!!

Written by Meguid El Nahas on Friday, 21 July 2017. Posted in OLA Blog

Glifozins & Cardioprotection: Another Myth in the Making...!!!
N Engl J Med. 2017 Jun 12. doi: 10.1056/NEJMoa1611925. [Epub ahead of print] Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes. Neal B1, Perkovic V1, Mahaffey KW1, de Zeeuw D1, Fulcher G1, Erondu...

Advantage of RAAS Blockade: Another Myth bites the dust...?!

Written by Meguid El Nahas on Monday, 03 July 2017. Posted in OLA Blog

Advantage of RAAS Blockade: Another Myth bites the dust...?!
Prof David Goldsmith Nephrol Dial Transplant (2017): 1–11 doi: 10.1093/ndt/gfx072 Effect of renin–angiotensin–aldosterone system blockade inadults with diabetes mellitus and advanced chronic...

To Treat or Not to Treat...?!

Written by Meguid El Nahas on Monday, 26 June 2017. Posted in OLA Blog

To Treat or Not to Treat...?!
https://www.thetimes.co.uk/article/professor-marcel-levi-dying-should-shun-treatment-and-take-final-holiday-pvsbkv0wj?shareToken=79a3e1f73a909362cfe132ca0b22a9ae Professor Marcel Levi: Dying should shun treatment and take final holiday......