OLA Blog

SPRINT: NOT SO FAST...

Written by Meguid El Nahas on Sunday, 17 January 2016. Posted in OLA Blog

SPRINT: NOT SO FAST...
N Engl J Med. 2015 Nov 26;373(22):2103-16. doi: 10.1056/NEJMoa1511939. Epub 2015 Nov 9. A Randomized Trial of Intensive versus Standard Blood-Pressure Control. SPRINT Research Group, Wright JT Jr, Williamson...

BREAKING NEWS! FDA Adds New Warnings on SGLT2 Inhibitors

Written by Jose Mario Franco de Oliveira on Saturday, 05 December 2015. Posted in OLA Blog

BREAKING  NEWS! FDA Adds New Warnings on SGLT2  Inhibitors
http://www.medpagetoday.com/Endocrinology/Diabetes/55035?isalert=1&uun=g257073d4708R5252063u&xid=NL_breakingnews_2015-12-04 EMPAGLIFLOZIN, CANAGLIFLOZIN, DAPAGLIFLOZIN, the so-called SGLT2 Inhbitors so far in the market (and others are...

Immunosuppression in IgA Nephropathy -

Written by arif khwaja on Friday, 04 December 2015. Posted in OLA Blog

Immunosuppression in IgA Nephropathy -
The evidence base for managing IgA Nephropathy has been poor based on small studies with variable control groups and standard of care. Until now KDIGO recommends aggressive ACEi/ARB therapy with a blood pressure target of 125/75mmHg....

intensive therapy in IgA nephropathy

Written by Pierre Delanaye on Thursday, 03 December 2015. Posted in OLA Blog

intensive therapy in IgA nephropathy
N Engl J Med. 2015 Dec 3;373(23):2225-2236. Intensive Supportive Care plus Immunosuppression in IgA Nephropathy. Rauen T1, Eitner F, Fitzner C, Sommerer C, Zeier M, Otte B, Panzer U, Peters...

ACE Inhibitors:Another nail in the coffin?

Written by Meguid El Nahas on Friday, 27 November 2015. Posted in OLA Blog

ACE Inhibitors:Another nail in the coffin?
Lancet Diabetes Endocrinol. 2015 Oct 21. pii: S2213-8587(15)00368-X. doi: 10.1016/S2213-8587(15)00368-X. [Epub ahead of print]Ramipril versus placebo in kidney transplant patients with proteinuria: a multicentre, double-blind, randomised...

Antimicrobial Prophylaxis and Renal Scarring in VUR: Still Hazy After all this Time...

Written by Neveen A Soliman on Thursday, 19 November 2015. Posted in OLA Blog

Antimicrobial Prophylaxis and Renal Scarring in VUR: Still Hazy After all this Time...
Vesicoureteral reflux (VUR) is the most common urologic finding in children, occurring in approximately 1 percent of newborns, and as many as 30 to 45 percent of young children with a urinary tract infection given the retrograde passage of urine...

SGLT2 Inhibitors in Diabetes: More than Glorified Diuretics?

Written by Meguid El Nahas on Monday, 09 November 2015. Posted in OLA Blog

SGLT2 Inhibitors in Diabetes: More than Glorified Diuretics?
N Engl J Med. 2015 Sep 17. [Epub ahead of print] Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes. Zinman B1, Wanner C, Lachin JM, Fitchett D, Bluhmki E, Hantel S, Mattheus...

SGLT2 Inhibitors in DN: More than a good diuretic?

Written by Meguid El Nahas on Monday, 09 November 2015. Posted in OLA Blog

SGLT2 Inhibitors in DN: More than a good diuretic?
N Engl J Med. 2015 Sep 17. [Epub ahead of print] Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes. Zinman B1, Wanner C, Lachin JM, Fitchett D, Bluhmki E, Hantel S, Mattheus...

PATHWAY INCOMPLETE?

Written by Meguid El Nahas on Thursday, 01 October 2015. Posted in OLA Blog

PATHWAY INCOMPLETE?
Lancet. 2015 Sep 18. pii: S0140-6736(15)00257-3. doi: 10.1016/S0140-6736(15)00257-3. [Epub ahead of print] Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension...

HD DAY OR NIGHT...WHAT MATTERS IS TIME!

Written by Meguid El Nahas on Tuesday, 29 September 2015. Posted in OLA Blog

HD DAY OR NIGHT...WHAT MATTERS IS TIME!
Nocturnal Dialysis May Provide Cardiovascular Benefits over Conventional Hemodialysis Conversion from conventional hemodialysis (CHD) to in-center nocturnal hemodialysis (INHD) was associated with a 14.2 g reduction in left ventricular mass after...