OLA Blog

Genotyping allografts: Dream or Reality?

Written by Meguid El Nahas on Saturday, 18 April 2015. Posted in OLA Blog

Genotyping allografts: Dream or Reality?
Growing evidence is implicating a genetic absis for CKD in African-Americans linked to mutations in the APOL1 gene. A genetic mutation that served sub-saharan Africans well some 10,000 years ago as it confered trypanolytic activity against...

FRAX in CKD

Written by Pierre Delanaye on Wednesday, 01 April 2015. Posted in OLA Blog

FRAX in CKD
Clin J Am Soc Nephrol. 2015 Feb 5. pii: CJN.06040614. [Epub ahead of print] Comparison of Fracture Risk Prediction among Individuals with Reduced and Normal Kidney Function. Naylor KL1, Garg AX2, Zou G3, Langsetmo...

The evidence or the individual?

Written by arif khwaja on Friday, 27 March 2015. Posted in OLA Blog

The evidence or the individual?
A few months ago I saw an 82 year old lady with very slowly progressive CKD4. She had T2DM, hypertension, a strong history of smoking and was referred by her GP as she had an eGFR of 29 mls/min ( compared to 35 mls/min 5 years ago). Her US showed...

Living kidney donation safety: a physiologic study...AT LEAST AND AFTER ALL!!!

Written by Pierre Delanaye on Friday, 13 March 2015. Posted in OLA Blog

Living kidney donation safety: a physiologic study...AT LEAST AND AFTER ALL!!!
    J Clin Invest. 2015 Mar 2;125(3):1311-8. doi: 10.1172/JCI78885. Epub  2015 Feb 17. Longitudinal study of living kidney donor glomerular dynamics after nephrectomy. Lenihan CR, Busque S, Derby G, Blouch K, Myers BD, Tan JC....

WORLD KIDNEY DAY 2015: AND DRINKING MORE WATER...?!

Written by Meguid El Nahas on Friday, 13 March 2015. Posted in OLA Blog

WORLD KIDNEY DAY 2015: AND DRINKING MORE WATER...?!
WORLD KIDNEY DAY 2015 AND KIDNEY HEALTH FOR ALL.... Seemed intricately linked to drinking water....every WKD celebration showed people...doctors...nurses...kidney patients...volunteers...shifting case after case of drinking water...bottled of...

RARE RENAL DISEASE: NEW FRONTIERS

Written by Neveen A Soliman on Sunday, 22 February 2015. Posted in OLA Blog

RARE RENAL DISEASE: NEW FRONTIERS
RARE RENAL DISEASES: NEW FRONTIERS Rare inherited kidney diseases are increasingly expanding thanks to next-generation sequencing techniques; with new disease entities being discovered and added to this rapidly growing list. Many of these...

Urinary creatinine: the forgotten parameter...

Written by Pierre Delanaye on Friday, 20 February 2015. Posted in OLA Blog

Urinary creatinine: the forgotten parameter...
PLoS One. 2014 Nov 17;9(11):e111949. doi: 10.1371/journal.pone.0111949. eCollection 2014. Decrease in urinary creatinine excretion in early stage chronic kidney disease. Tynkevich E1, Flamant M2, Haymann JP3, Metzger...

RESEARCH CULTURE: All too often Castles built on Sand...

Written by Meguid El Nahas on Wednesday, 17 December 2014. Posted in OLA Blog

RESEARCH CULTURE: All too often Castles built on Sand...
IN THE LANCET THIS WEEK: What is high quality science? Rigorous, accurate, original, honest, and transparent were the words selected by scientists who took part in the UK Nuffield Council on Bioethics' project to assess the ethical...

SHORTAGE OF NEPHROLOGISTS: IS REGENERATIVE MEDICINE THE ANSWER?

Written by Meguid El Nahas on Wednesday, 17 December 2014. Posted in OLA Blog

SHORTAGE OF NEPHROLOGISTS: IS REGENERATIVE MEDICINE THE ANSWER?
ROFESSOR KIM SOLEZ (CANADA) WROTE: IN aswer to the shortage of Nephrology trainees in US http://ajkdblog.org/…/a-new-nephrologic-syndrome-acute-fel…/  Highly significant and related to what I have been writing and saying...

AUTOANTIBODIES IN IMN: A PARAPHENOMENON?

Written by Meguid El Nahas on Monday, 15 December 2014. Posted in OLA Blog

AUTOANTIBODIES IN IMN: A PARAPHENOMENON?
N Engl J Med. 2014 Dec 11;371(24):2277-2287. Epub 2014 Nov 13. Thrombospondin Type-1 Domain-Containing 7A in Idiopathic Membranous Nephropathy. Tomas NM1, Beck LH Jr, Meyer-Schwesinger C, Seitz-Polski B, Ma...