OLA Blog

Microalbuminuria: The End of an Era?!

Written by Meguid El Nahas on Monday, 14 April 2014. Posted in OLA Blog

Microalbuminuria: The End of an Era?!
Kidney Int. 2014 Apr 9. doi: 10.1038/ki.2014.98. [Epub ahead of print] 'Progressive diabetic nephropathy. How useful is microalbuminuria? Macisaac RJ1, Ekinci EI2, Jerums G3.  Abstract The concept of...

CKD "Progression" and Physical Exercise: Its all in the Surrogate Biomarker!

Written by Meguid El Nahas on Tuesday, 08 April 2014. Posted in OLA Blog

CKD "Progression" and Physical Exercise: Its all in the Surrogate Biomarker!
A recent paper in the Journal of the American Soceity of Nephrology has linked physical exercise  with a slower rate of eGFR decline in patients with CKD3. Abstract Physical activity may counteract metabolic disturbances that promote...

HOW TO ASSESS CKD PROGRESSION?

Written by Meguid El Nahas on Monday, 07 April 2014. Posted in OLA Blog

HOW TO ASSESS CKD PROGRESSION?
An excellent editorial by Steven Rosansky and Richard Glassock review issues related to the estimation of CKD progression in renoprotection drug trials. http://www.ncbi.nlm.nih.gov/pubmed/24682115 The authors examine the currently used...

CYSTINOSIS GAP!

Written by Meguid El Nahas on Monday, 07 April 2014. Posted in OLA Blog

CYSTINOSIS GAP!
A letter to the editor in this month NEJM: http://www.ncbi.nlm.nih.gov/pubmed/24693916 highlights the difference between the outcome of Nephropathic Cystinosis in developed and developing countries. A survey undertaken by the authors in 17...

The end of the road for renal denervation?

Written by arif khwaja on Friday, 04 April 2014. Posted in OLA Blog

The end of the road for renal denervation?
There has been much interest in the last couple of years in the potential of renal denervation to manage resistant hypertension particularly after the SYMPLICITY-HTN-2 study was published in the Lancet several years ago. There have been a number...

FSGS and GENETIC TESTING - Prof Neveen Soliman

Written by Meguid El Nahas on Sunday, 16 March 2014. Posted in OLA Blog

FSGS and GENETIC TESTING - Prof Neveen Soliman
Kidney Int. 2014 Mar 5. doi: 10.1038/ki.2014.48. [Epub ahead of print]Genetic testing for nephrotic syndrome and FSGS in the era of next-generation sequencing.Brown EJ1, Pollak MR2, Barua M3.Author informationAbstractThe haploid human genome is...

HOW CAN I TRUST GUIDELINES...DR ALHAMMADY.

Written by Meguid El Nahas on Sunday, 16 February 2014. Posted in OLA Blog

HOW CAN I TRUST GUIDELINES...DR ALHAMMADY.
Blog By Dr Sherif AlHammady (Edited by Prof El Nahas)   My advice to you if you are optimistic about the era of guidelines is to read the BMJ article: WHY WE CAN NOT TRUST CLINICAL GUIDELINES? http://www.ncbi.nlm.nih.gov/pubmed/23900822...

Shades of Heart Failure in CKD?! Dr Shanmuga KUMAR

Written by Meguid El Nahas on Sunday, 16 February 2014. Posted in OLA Blog

Shades of Heart Failure in CKD?! Dr Shanmuga KUMAR
Dr Shanmuga KUMAR (Sheffield Kidney Institute) wrote:  A recent paper[1] assessing exercise capacity of patients with chronic kidney disease (CKD) has rekindled some interest in the application of cardiopulmonary exercise testing (CPX) in...

Outcome studies in living kidney donors

Written by Will McKane on Monday, 03 February 2014. Posted in OLA Blog

Outcome studies in living kidney donors
Nephrologists and transplant surgeons have grown up believing that living kidney donation is a safe procedure with low short and long term risk for the donor. Cohort studies comparing donors with the general population have demonstrated equivalent...

Negative RCTs in HD: Are we closing the Dialysis (Mortality) door after the Horse (Complications) has bolted...?!

Written by Meguid El Nahas on Thursday, 30 January 2014. Posted in OLA Blog

Negative RCTs in HD: Are we closing the Dialysis (Mortality) door after the Horse (Complications) has bolted...?!
J Am Soc Nephrol. 2013 Dec;24(12):1934-43. doi: 10.1681/ASN.2013060632. Epub 2013 Oct 17. Evidence-based cardiology in hemodialysis patients. Allon M.  This is an interesting review article in JASN December 2014 reviewing...
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