OLA Blog

RCTs in CKDs: A Waste of Time?

Written by Meguid El Nahas on Sunday, 21 May 2017. Posted in OLA Blog

RCTs in CKDs: A Waste of Time?
Many Nephrologists seem preoccupied by planning randomised control trials (RCTs) to slow the progression of CKD (Chronic Kidney Disease)... What a folly...!!!! As if CKD is a disease...it is a simplified definition of reduced kidney function...

Cystic Kidney Diseases

Written by Neveen A Soliman on Saturday, 20 May 2017. Posted in OLA Blog

Figure 1. Renal ultrasound scans of: (a) ARPKD; (b) ADPKD; (c) Juvenile NPHP; (d) Bilateral cystic dysplastic kidneys
Clinical and ultrasonographical characterization of childhood cystic kidney diseases in Egypt Ren Fail. 2014 Jun;36(5):694-700. doi: 10.3109/0886022X.2014.883996 http://www.tandfonline.com/doi/full/10.3109/0886022X.2014.883996 From authors...

Is KI Fit for Purpose?

Written by Meguid El Nahas on Monday, 15 May 2017. Posted in OLA Blog

Is KI Fit for Purpose?
        I read this month (May 2017) Kidney International whilst in an emerging country teaching to emerging doctors on clinical aspects of Kidney Disease. Once more, I found very few articles of relevance to those...

This Month (May 2017) in KI: Obesity and CKD

Written by Meguid El Nahas on Monday, 15 May 2017. Posted in OLA Blog

This Month (May 2017) in KI: Obesity and CKD
Obesity and new onset of CKD: https://www.ncbi.nlm.nih.gov/pubmed/28187985 Obesity but not overweight increases risk of CKD (eGFR <60 and albuminuria) in the general population. A systematic review and Meta-analysis of 39 cohorts, 630,677...

Last Month in Nephrology...by Prof Tukaram Jamale

Written by Meguid El Nahas on Friday, 05 May 2017. Posted in OLA Blog

Last Month in Nephrology...by Prof Tukaram Jamale
April-May 2017 JASN  Pregnancy outcomes in recovered AKI  In a study of 105 pregnancies classified as rAKI (pregnant women with history of recovered AKI) were compared with 24640 control pregnancies-authors noted that...

Epigenetic modifications in ANCA-associated vasculitis (AAV)

Written by Neveen A Soliman on Wednesday, 05 April 2017. Posted in OLA Blog

Epigenetic modifications in ANCA-associated vasculitis (AAV)
AAV is a relapsing and remitting autoimmune disease characterized by vascular inflammation and organ damage. -       Generally characterized by circulating ANCA, reactive to proteinase 3 (PR3) or myeloperoxidase...

Have you washed your hands?

Written by Martin Wilkie on Monday, 03 April 2017. Posted in OLA Blog

Have you washed your hands?
Given that infection control is a key issue in dialysis units, and that antimicrobial resistance is an international threat, why then do we not routinely teach all centre-based dialysis patients to wash their hands when they come for dialysis?...

Vitamin D Deficiency: A Global or a Bogus Pandemic

Written by Meguid El Nahas on Sunday, 02 April 2017. Posted in OLA Blog

Vitamin D Deficiency: A Global or a Bogus Pandemic
http://www.nejm.org/doi/pdf/10.1056/NEJMp1608005 N Engl J Med. 2016 Nov 10;375(19):1817-1820. Vitamin D Deficiency - Is There Really a Pandemic? Manson JE1, Brannon PM1, Rosen CJ1, Taylor CL1.   Prof Arif...

CKDu, CINAC, KDUCAL; A Nephropathy looking for a name....

Written by Meguid El Nahas on Friday, 31 March 2017. Posted in OLA Blog

CKDu, CINAC, KDUCAL; A Nephropathy looking for a name....
Am J Kidney Dis. 2017 Apr;69(4):552. doi: 10.1053/j.ajkd.2016.09.029. Kidney Disease of Unknown Cause in Agricultural Laborers (KDUCAL) Is a Better Term to Describe Regional and Endemic Kidney Diseases Such as Uddanam Nephropathy....

WKD: Propaganda or Facts?!

Written by Meguid El Nahas on Wednesday, 08 March 2017. Posted in OLA Blog

WKD: Propaganda or Facts?!
The 2017 WKD theme is OBESITY & CKD implying a link between the incidence, progression and outcomes of CKD and Obesity. Presumably a harmful link...?! Whilst I am aware of links between Obesity and the Metabolic syndrome, and between the...