OLA Blog

SPRINT Cost Effectiveness: Lower BP or Better Diuretic Therapy?!

Written by Meguid El Nahas on Tuesday, 05 September 2017. Posted in OLA Blog

SPRINT Cost Effectiveness: Lower BP or Better Diuretic Therapy?!
 N Engl J Med. 2017 Aug 24;377(8):745-755. doi: 10.1056/NEJMsa1616035. Cost-Effectiveness of Intensive versus Standard Blood-Pressure Control....

Nephrology Guidelines: Are they Safe...?!

Written by Meguid El Nahas on Friday, 11 August 2017. Posted in OLA Blog

Nephrology Guidelines: Are they Safe...?!
Are Nephrology Guidelines fit  for purpose or are they: 1. Too US Centric like the latest KDIGO Kidney Donors Guidelines 2. Too overlooking of low and middle economies healthcare priorities... 3. Too Pharma Friendly... 4. Too "KOL"...

Myths in Nephrology

Written by Meguid El Nahas on Wednesday, 26 July 2017. Posted in OLA Blog

Myths in Nephrology
A Myth is a widely held but false belief or idea. Nephrology is full of Myths that are peddled and believed without valid supporting evidence; some are based on animal experimentation without supporting evidence in man. Some are simply...

Glifozins & Cardioprotection: Another Myth in the Making...!!!

Written by Meguid El Nahas on Friday, 21 July 2017. Posted in OLA Blog

Glifozins & Cardioprotection: Another Myth in the Making...!!!
N Engl J Med. 2017 Jun 12. doi: 10.1056/NEJMoa1611925. [Epub ahead of print] Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes. Neal B1, Perkovic V1, Mahaffey KW1, de Zeeuw D1, Fulcher G1, Erondu...

Advantage of RAAS Blockade: Another Myth bites the dust...?!

Written by Meguid El Nahas on Monday, 03 July 2017. Posted in OLA Blog

Advantage of RAAS Blockade: Another Myth bites the dust...?!
Prof David Goldsmith Nephrol Dial Transplant (2017): 1–11 doi: 10.1093/ndt/gfx072 Effect of renin–angiotensin–aldosterone system blockade inadults with diabetes mellitus and advanced chronic...

To Treat or Not to Treat...?!

Written by Meguid El Nahas on Monday, 26 June 2017. Posted in OLA Blog

To Treat or Not to Treat...?!
https://www.thetimes.co.uk/article/professor-marcel-levi-dying-should-shun-treatment-and-take-final-holiday-pvsbkv0wj?shareToken=79a3e1f73a909362cfe132ca0b22a9ae Professor Marcel Levi: Dying should shun treatment and take final holiday......

To Treat or Not to Treat...?!

Written by Meguid El Nahas on Monday, 26 June 2017. Posted in OLA Blog

To Treat or Not to Treat...?!
https://www.thetimes.co.uk/article/professor-marcel-levi-dying-should-shun-treatment-and-take-final-holiday-pvsbkv0wj?shareToken=79a3e1f73a909362cfe132ca0b22a9ae Professor Marcel Levi: Dying should shun treatment and take final holiday......

More or Less Nephrons...

Written by Meguid El Nahas on Thursday, 22 June 2017. Posted in OLA Blog

More or Less Nephrons...
I read more than once this paper and failed to understand it... N Engl J Med. 2017 Jun 15;376(24):2349-2357. doi: 10.1056/NEJMoa1614329. Single-Nephron Glomerular Filtration Rate in Healthy Adults. Denic A1, Mathew...

PRECISION MEDICINE: Whats in a Name?!

Written by Meguid El Nahas on Tuesday, 30 May 2017. Posted in OLA Blog

PRECISION MEDICINE: Whats in a Name?!
PRECISION MEDICINE, a term that has crept into the medical lexicom that baffles me... I am told that PRECISION MEDICINE is: "...based on accurate diagnosis and tailored interventions through the use of improved diagnostic tests and clinical...

Precision Nephrology in Genomic Era

Written by Neveen A Soliman on Sunday, 28 May 2017. Posted in OLA Blog

Precision Nephrology in Genomic Era
Chronic Kidney Disease (CKD) is a major global health problem with significant morbidity and mortality and high economic burden in various geographic communities. During the 20th century, nephrology clinical practice witnessed significant...