The Utility of Cardiopulmonary Exercise Testing for the Prediction of Outcomes in Ambulatory Children With Dilated Cardiomyopathy

Written by Transplantation on Friday, 22 September 2017.

The Utility of Cardiopulmonary Exercise Testing for the Prediction of Outcomes in Ambulatory Children With Dilated Cardiomyopathy
Background: Unlike adult patients, the utility of cardiopulmonary exercise testing (CPET) in children as a prognostic tool is unclear. We sought to...

CMV-Specific T Cell Monitoring Offers Superior Risk Stratification of CMV-Seronegative Kidney Transplant Recipients of a CMV-Seropositive Donor

Written by Transplantation on Friday, 22 September 2017.

CMV-Specific T Cell Monitoring Offers Superior Risk Stratification of CMV-Seronegative Kidney Transplant Recipients of a CMV-Seropositive Donor
Background: Detectable cytomegalovirus (CMV)-specific T cells in CMV-seronegative kidney transplant recipients (KTRs) have been attributed to an...

Gender Equity in Transplantation: A Report from the Women in Transplantation Workshop of The Transplantation Society of Australia and New Zealand

Written by Transplantation on Friday, 22 September 2017.

Gender Equity in Transplantation: A Report from the Women in Transplantation Workshop of The Transplantation Society of Australia and New Zealand
The Science in Australia and Gender Equity (SAGE) Pilot,1 a program based on the Athena Scientific Women's Academic Network Charter, was launched...

Cardiovascular Parameters to 2 years After Kidney Transplantation Following Early Switch to Everolimus Without Calcineurin Inhibitor Therapy: An Analysis of the Randomized ELEVATE Study

Written by Transplantation on Friday, 22 September 2017.

Cardiovascular Parameters to 2 years After Kidney Transplantation Following Early Switch to Everolimus Without Calcineurin Inhibitor Therapy: An Analysis of the Randomized ELEVATE Study
Background: Mammalian target of rapamycin inhibitors may confer cardioprotective advantages, but clinical data are limited.Methods: In the...

BOS Is Associated With Increased Cytotoxic Proinflammatory CD8 T, NKT-Like, and NK Cells in the Small Airways

Written by Transplantation on Thursday, 21 September 2017.

BOS Is Associated With Increased Cytotoxic Proinflammatory CD8 T, NKT-Like, and NK Cells in the Small Airways
Background: Immunosuppression therapy after lung transplantation fails to prevent bronchiolitis obliterans syndrome (BOS) in many patients,...

Depleting Antibody Induction and Kidney Transplant Outcomes: A Paired Kidney Analysis

Written by Transplantation on Thursday, 21 September 2017.

Depleting Antibody Induction and Kidney Transplant Outcomes: A Paired Kidney Analysis
Background: Induction immunosuppression decreases the risk for acute rejection and improves graft outcomes in kidney transplant recipients (KTRs)....

Insights in Transplanting Complex Pediatric Renal Recipients With Vascular Anomalies

Written by Transplantation on Thursday, 21 September 2017.

Insights in Transplanting Complex Pediatric Renal Recipients With Vascular Anomalies
Background: Children with end-stage kidney disease may have coexisting iatrogenic or congenital vascular anomalies making transplantation...

Belatacept Compared With Tacrolimus for Kidney Transplantation: A Propensity Score Matched Cohort Study

Written by Transplantation on Friday, 22 September 2017.

Belatacept Compared With Tacrolimus for Kidney Transplantation: A Propensity Score Matched Cohort Study
Background: Although tacrolimus is the basis of most maintenance immunosuppression regimens for kidney transplantation, concerns about toxicity...

Pancreas Transplantation From Pediatric Donors: A United Network for Organ Sharing Registry Analysis

Written by Transplantation on Friday, 22 September 2017.

Pancreas Transplantation From Pediatric Donors: A United Network for Organ Sharing Registry Analysis
Background: Pancreas grafts from pediatric donors are still considered “not ideal.” Perceived concerns are related to low islet mass and...

Treatment of Acute Antibody-Mediated Renal Allograft Rejection With Cyclophosphamide

Written by Transplantation on Friday, 22 September 2017.

Treatment of Acute Antibody-Mediated Renal Allograft Rejection With Cyclophosphamide
Background: Antibody-mediated rejection (AMR) is a major risk for renal allograft survival. Throughout decades, cyclophosphamide treatment has been...

Long-term Outcomes of Kidney Transplantation in Patients With High Levels of Preformed DSA: The Necker High-Risk Transplant Program

Written by Transplantation on Thursday, 21 September 2017.

Long-term Outcomes of Kidney Transplantation in Patients With High Levels of Preformed DSA: The Necker High-Risk Transplant Program
Background: There is an increasing number of anti-HLA sensitized and highly sensitized renal transplant candidates on waiting lists, and the...

Anti-Gal and Anti-Neu5Gc Responses in Nonimmunosuppressed Patients After Treatment With Rabbit Antithymocyte Polyclonal IgGs

Written by Transplantation on Thursday, 21 September 2017.

Anti-Gal and Anti-Neu5Gc Responses in Nonimmunosuppressed Patients After Treatment With Rabbit Antithymocyte Polyclonal IgGs
Background: Polyclonal antihuman thymocyte rabbit IgGs (antithymocyte globulin [ATG]) are popular immunosuppressive drugs used to prevent or treat...

Harnessing Advances in T Regulatory Cell Biology for Cellular Therapy in Transplantation

Written by Transplantation on Thursday, 21 September 2017.

Harnessing Advances in T Regulatory Cell Biology for Cellular Therapy in Transplantation
Abstract: Cellular therapy with CD4+FOXP3+ T regulatory (Treg) cells is a promising strategy to induce tolerance after solid-organ transplantation...

Liver Transplantation in the Obese Cirrhotic Patient

Written by Transplantation on Thursday, 21 September 2017.

Liver Transplantation in the Obese Cirrhotic Patient
Abstract: Despite the rapidly increasing prevalence of obesity in the transplant population, the optimal management of obese liver transplant...